effects of hyperbilirubinemia on auditory brainstem response of neonates treated with phototherapy
نویسندگان
چکیده
introduction: one of the most common pathologies in neonates is hyperbilirubinemia, which is a good marker for damage to the central nervous system. the sensitivity of the auditory system to bilirubin has been previously documented, with much discrepancy in its effects on auditory brainstem response results. thus the objective of this study was to evaluate the effects of hyperbilirubinemia on auditory brainstem response of neonates treated with phototherapy. materials and methods: forty-two term neonates with hyperbilirubinemia, who underwent phototherapy participated in this cross sectional study. the recording of auditory brainstem response was made shortly after confirming that the total serum bilirubin level was greater than 15 µg/dl. latency of waves i, iii, v and inter-peak latencies of the waves were measured. to test the hypothesis about the difference of means between the two groups, continuous variables were compared using either the t-test (normal distribution) or the mann-whitney test (non-normal distribution). results: there was a significant increase in the absolute latencies of waves iii and v, and i-iii and i-v inter-peak latencies of the sample group compared to the control group in both ears (p<0.05). however, wave i absolute latency and iii-v inter-peak interval did not show a significant difference between the two study groups (p>0.05). conclusion: the results of this study underline the importance of the auditory brainstem response test as an efficient tool for monitoring the auditory brainstem pathway in neonates who are at risk of neurotoxicity and for diagnosing the earliest stages of auditory damage caused by high levels of bilirubin.
منابع مشابه
Effects of Hyperbilirubinemia on Auditory Brainstem Response of Neonates Treated with Phototherapy
Introduction: One of the most common pathologies in neonates is hyperbilirubinemia, which is a good marker for damage to the central nervous system. The sensitivity of the auditory system to bilirubin has been previously documented, with much discrepancy in its effects on Auditory Brainstem Response results. Thus the objective of this study was to evaluate the effects of hyperbilirubinemia on ...
متن کاملEffects of Hyperbilirubinemia on Auditory Brainstem Response of Neonates Treated with Phototherapy.
INTRODUCTION One of the most common pathologies in neonates is hyperbilirubinemia, which is a good marker for damage to the central nervous system. The sensitivity of the auditory system to bilirubin has been previously documented, with much discrepancy in its effects on Auditory Brainstem Response results. Thus the objective of this study was to evaluate the effects of hyperbilirubinemia on Au...
متن کاملBrainstem auditory evoked response in newborns with hyperbilirubinemia.
OBJECTIVE To determine the initial Brainstem Auditory Evoked Response (BAER) abnormalities in neonates with hyperbilirubinemia and the possible reversibility of abnormal BAER after therapy. DESIGN Prospective cohort study. SETTING Tertiary care hospital. SUBJECTS 30 term neonates with hyperbilirubinemia (S. bilirubin < 15 mg/dl) as cases and 25 normal term neonates as controls. METHODS ...
متن کاملEffects of Body Massage on Response to Phototherapy in Neonatal Hyperbilirubinemia: A Randomized Clinical Trial
Background: Massage therapy has been commonly practiced as a traditional complementary therapy in neonates. This study was designed to evaluate the effects of massage on decreasing bilirubin levels in infants undergoing phototherapy. Materials and Methods A total of 60 term icteric infan...
متن کاملThe Relationship between Severe Hyperbilirubinemia and Abnormal Auditory Brainstem Response in children
Abstract:Background : Hyperbilirubinemia is one of the most common cause of congenital sensory neuronal hearing loss. These patients are screened by auditory brainstem response (ABR) test at bilirubin levels higher than 1% of gestational weight. Aim: to determine whether hyperbilirubinemia less than 1% of gestational weight could induce hearing loss and abnormal auditory brainstem response (ABR...
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عنوان ژورنال:
iranian journal of otorhinolaryngologyجلد ۲۸، شماره ۱، صفحات ۲۳-۲۹
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